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Gene

alx1

ID
ZDB-GENE-050419-191
Name
ALX homeobox 1
Symbol
alx1 Nomenclature History
Previous Names
  • si:ch211-154h20.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within embryonic cranial skeleton morphogenesis and neural crest cell migration. Predicted to be located in nucleus. Is expressed in head; head mesenchyme; neural crest; pectoral fin bud; and presumptive cephalic mesoderm. Orthologous to human ALX1 (ALX homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Dee et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Dee et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alx1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Frontonasal dysplasia 3 613456
Associated With alx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR003654 OAR domain
Family IPR033209 ALX homeobox protein 1
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length ALX homeobox protein 1 Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily OAR domain
UniProtKB:Q1LVQ7 320
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations