Gene

ppp3cb

ID
ZDB-GENE-050417-406
Name
protein phosphatase 3, catalytic subunit, beta isozyme
Symbol
ppp3cb Nomenclature History
Previous Names
  • wu:fq19c08
  • zgc:110141
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Predicted to be involved in calcineurin-NFAT signaling cascade. Predicted to localize to calcineurin complex and cytosol. Human ortholog(s) of this gene implicated in infantile or early childhood epileptic encephalopathy 1. Is expressed in hatching gland; integument; nervous system; and pharyngeal arch. Orthologous to human PPP3CA (protein phosphatase 3 catalytic subunit alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppp3cb Human Ortholog
No data available
Associated With ppp3cb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
Domain IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Domain IPR041751 PP2B, metallophosphatase domain
Family IPR043360 PP2B
Homologous_superfamily IPR029052 Metallo-dependent phosphatase-like
Domain Details Per Protein
Protein Length Calcineurin-like phosphoesterase domain, ApaH type Metallo-dependent phosphatase-like PP2B PP2B, metallophosphatase domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
UniProtKB:B2GS58 511
UniProtKB:Q568R4 511
UniProtKB:A0A0R4IZT7 192
UniProtKB:E7F169 511
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations