ZFIN ID: ZDB-GENE-050417-401
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Gene Name: ATG16 autophagy related 16-like 1 (S. cerevisiae)
Gene Symbol: atg16l1    Nomenclature History

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Previous Names: fb57e05, wu:fb57e05, zgc:110147

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to be involved in autophagosome assembly and negative stranded viral RNA replication. Predicted to localize to the autophagosome membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1).
Genome Resources: Alliance (1),  Gene:550552 (1),  Ensembl(GRCz11):ENSDARG00000099430 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110147]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH atg16l1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
inflammatory bowel disease 10 Alliance {Inflammatory bowel disease (Crohn disease) 10} 611081
DISEASE ASSOCIATED WITH atg16l1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process autophagosome assembly (more)
Cellular Component autophagosome membrane (more)
Molecular Function molecular_function (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR013923 Autophagy-related protein 16
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atg16l1-201 (1)    Ensembl 1866
Select Tool
atg16l1-202 (1)    Ensembl 4727
Select Tool
Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atg16l1 No data available
MARKER RELATIONSHIPS
atg16l1 Contained in: [Fosmid] CH1073-430K5 (1), ZFOS-761D5 (1)
atg16l1 Encodes: [EST] fb57e05
[cDNA] MGC:110147 (1), MGC:191307 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001017854 (1) 1369 nt
Select Tool
Genomic GenBank:CU929115 (1) 42253 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IBY0 (1) 621 aa
Select Tool
Sequence Information (all 21)
ORTHOLOGY for atg16l1 ( Chr: 15 )
CITATIONS (17)