Gene

atg16l1

ID

ZDB-GENE-050417-401

Name

ATG16 autophagy related 16-like 1 (S. cerevisiae)

Symbol

atg16l1 Nomenclature History

Previous Names

fb57e05
wu:fb57e05
zgc:110147

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to be involved in autophagosome assembly and negative stranded viral RNA replication. Predicted to localize to autophagosome membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Is expressed in intestine. Orthologous to human ATG16L1 (autophagy related 16 like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

MGC:110147 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atg16l1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
inflammatory bowel disease 10	Alliance	{Inflammatory bowel disease (Crohn disease) 10}	611081

Associated With atg16l1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR013923	Autophagy-related protein 16
Domain	IPR017986	WD40-repeat-containing domain
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Length	Autophagy-related protein 16	G-protein beta WD-40 repeat	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A0R4IWT6 InterPro	330
UniProtKB:Q568R2 InterPro	330
UniProtKB:A0A0R4IBY0 InterPro	621
UniProtKB:A0A0R4IP97 InterPro	606
UniProtKB:A0A0R4IRC0 InterPro	233

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	atg16l1-201 (1) Ensembl	1866 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	atg16l1-202 (1) Ensembl	4727 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations