Gene

tfap2b

ID
ZDB-GENE-050417-394
Name
transcription factor AP-2 beta
Symbol
tfap2b Nomenclature History
Previous Names
  • ap2b (1)
  • si:dkey-5e16.1 (1)
  • zgc:110163 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in cartilage development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Char syndrome and patent ductus arteriosus. Is expressed in several structures, including basal plate midbrain region; nervous system; pharyngeal arch; pronephros; and ventral mesoderm. Orthologous to human TFAP2B (transcription factor AP-2 beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tfap2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Char syndrome Alliance Char syndrome 169100
Patent ductus arteriosus 2 617035
Associated With tfap2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013854 Transcription factor AP-2, C-terminal
Family IPR004979 Transcription factor AP-2
Family IPR008122 Transcription factor AP-2 beta
Domain Details Per Protein
Protein Length Transcription factor AP-2 Transcription factor AP-2 beta Transcription factor AP-2, C-terminal
UniProtKB:Q561Y4 266
UniProtKB:Q4TTV4 439
UniProtKB:A0A286Y8U3 439
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations