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General Information
ZIRC
ZFIN ID: ZDB-GENE-050417-357
Gene Name: twist family bHLH transcription factor 1b
Gene Symbol: twist1b
Sequence Ontology ID : SO:0001217

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Previous Names: twist1a (2), zgc:110208 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits enhancer sequence-specific DNA binding activity. Involved in several processes, including pharyngeal system development; regulation of bone mineralization; and sprouting angiogenesis. Human  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
el570 Small Deletion Unknown Unknown TALEN
sh423 Small Deletion Unknown Frameshift, Premature Stop CRISPR
Targeting reagents:
DISEASE ASSOCIATED WITH twist1b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
craniosynostosis Craniosynostosis 1 123100
Saethre-Chotzen syndrome Saethre-Chotzen syndrome with or without eyelid anomalies 101400
Sweeney-Cox syndrome Sweeney-Cox syndrome 617746
Robinow-Sorauf syndrome 180750
DISEASE ASSOCIATED WITH twist1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Molecular Function cis-regulatory region sequence-specific DNA binding (more)
GO Terms (all 6)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA twist1b-201 (1) 1215
twist1b-202 (1) 944
 Withdrawn Transcriptsextinct
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM twist1b
MARKER RELATIONSHIPS
twist1b Contained in: [BAC] CH73-181M7 (1) (order this), DKEY-10F11 (order this)
twist1b Encodes: [cDNA] MGC:110208 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001017820 (1) 1226 bp
Genomic GenBank:BX005389 (1) 221363 bp Blast at MegaBLAST
Polypeptide UniProtKB:Q568M7 (1) 169 aa
Sequence Clusters UniGene:90894 (1)
Sequence Information (all 17)
ORTHOLOGY for twist1b ( Chr: 16 )
CITATIONS (38)