Gene
rras2
- ID
- ZDB-GENE-050417-352
- Name
- RAS related 2
- Symbol
- rras2 Nomenclature History
- Previous Names
-
- wu:fc47b08
- zgc:110215
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction. Predicted to localize to plasma membrane. Is expressed in several structures, including adaxial cell; head mesenchyme; hindbrain neural plate; musculature system; and notochord. Human ortholog(s) of this gene implicated in Noonan syndrome. Orthologous to human RRAS2 (RAS related 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110215 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Noonan syndrome 12 | 618624 | ||
Ovarian carcinoma |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTPase, Ras-type | Small GTP-binding protein domain |
---|---|---|---|---|---|
UniProtKB:Q568M0
|
202 |
Interactions and Pathways
No data available
Plasmids
No data available