Gene

capn2l

ID
ZDB-GENE-050417-341
Name
calpain 2, (m/II) large subunit, like
Symbol
capn2l Nomenclature History
Previous Names
  • wu:fb09d04
  • xx:hac23b03
  • zgc:112420
  • zgc:92480
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis and regulation of cytoskeleton organization. Predicted to localize to cytoplasm. Is expressed in ectoderm; epidermis; lateral line ganglion; pectoral fin; and pharynx. Orthologous to human CAPN2 (calpain 2).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With capn2l Human Ortholog
No data available
Associated With capn2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR001300 Peptidase C2, calpain, catalytic domain
Domain IPR002048 EF-hand domain
Domain IPR022682 Peptidase C2, calpain, large subunit, domain III
Domain IPR022683 Peptidase C2, calpain, domain III
Domain IPR033883 Calpain subdomain III
Family IPR022684 Peptidase C2, calpain family
Family IPR029539 Calpain-2
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR036213 Calpain large subunit, domain III superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Calpain-2 Calpain large subunit, domain III superfamily Calpain subdomain III Cysteine peptidase, cysteine active site EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Papain-like cysteine peptidase superfamily Peptidase C2, calpain, catalytic domain Peptidase C2, calpain, domain III Peptidase C2, calpain family Peptidase C2, calpain, large subunit, domain III
UniProtKB:Q561U0 700
UniProtKB:A0A0N4SUE6
UniProtKB:Q6DFZ8 700
UniProtKB:A8KC46 700
UniProtKB:F6NUF6 711
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations