ZFIN ID: ZDB-GENE-050417-304
Gene Name: actin related protein 2/3 complex inhibitor
Gene Symbol: arpin    Nomenclature History

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Previous Names: si:ch211-200o3.3, zgc:112432

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Involved in directional locomotion and negative regulation of cell migration. Predicted to localize to the lamellipodium. Is expressed in intestinal bulb. Orthologous to several human genes including ARPIN (actin related protein 2/3 complex inhibitor).
Genome Resources: Alliance (1),  Gene:550477 (1),  Ensembl(GRCz11):ENSDARG00000041085 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2004 [MGC:112432]
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9386 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arpin N/A 1
    DISEASE ASSOCIATED WITH arpin HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arpin VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process directional locomotion (more)
    Cellular Component cell projection (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR018889 Arpin
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arpin-201 (1)    Ensembl 1001
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arpin No data available
    MARKER RELATIONSHIPS
    arpin Contained in: [BAC] CH211-200O3 (1)
    arpin Encodes: [cDNA] MGC:112432 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017780 (1) 1002 bp
    Genomic GenBank:BX548061 (1) 84142 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RR95 (1) 226 aa
    Sequence Information (all 12)
    ORTHOLOGY for arpin ( Chr: 18 )
    CITATIONS (22)