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Gene

eed

ID
ZDB-GENE-050417-287
Name
embryonic ectoderm development
Symbol
eed Nomenclature History
Previous Names
  • zgc:112509
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to contribute to histone methyltransferase activity (H3-K27 specific) and nucleosome binding activity. Predicted to be involved in chromatin silencing and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within histone methylation. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex. Is expressed in several structures, including eye; gonad; heart; intestine; and midbrain hindbrain boundary. Orthologous to human EED (embryonic ectoderm development).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eed Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cohen-Gibson syndrome 617561
Associated With eed Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR017986 WD40-repeat-containing domain
Family IPR037352 Polycomb protein EED
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Polycomb protein EED WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:B2GPR4 426
UniProtKB:Q566T0 443
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations