Gene
eed
- ID
- ZDB-GENE-050417-287
- Name
- embryonic ectoderm development
- Symbol
- eed Nomenclature History
- Previous Names
-
- zgc:112509
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to contribute to histone methyltransferase activity (H3-K27 specific) and nucleosome binding activity. Predicted to be involved in chromatin silencing and negative regulation of transcription by RNA polymerase II. Predicted to localize to ESC/E(Z) complex. Is expressed in several structures, including eye; gonad; heart; intestine; and midbrain hindbrain boundary. Orthologous to human EED (embryonic ectoderm development).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112509 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Raby et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cohen-Gibson syndrome | 617561 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR051243 | Polycomb group WD repeat-containing protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Polycomb group WD repeat-containing protein | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1N587
|
441 | |||||
|
UniProtKB:Q566T0
|
443 |
Interactions and Pathways
No data available
Plasmids
No data available