header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050417-27
Gene Name: exosome component 2
Gene Symbol: exosc2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fa97b01, wu:fa97b01, zgc:110117

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in RNA metabolic process. Predicted to localize to the cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in immature eye; midbrain hindbrain boundary; and optic tectum. Orthologous to human EXOSC2 (exosome component 2).
Genome Resources: Alliance (1),  Gene:550234 (1),  Ensembl(GRCz11):ENSDARG00000028688 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6903240]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10662 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33781 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40616 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH exosc2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Short stature, hearing loss, retinitis pigmentosa, and distinctive facies 617763
    DISEASE ASSOCIATED WITH exosc2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process CUT catabolic process (more)
    Cellular Component exosome (RNase complex) (more)
    Molecular Function RNA binding (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA exosc2-201 (1)    Ensembl 1032
    ncRNA exosc2-002 (1)    Ensembl 782
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM exosc2 No data available
    MARKER RELATIONSHIPS
    exosc2 Contained in: [BAC] CH73-64K8 (1) (order this)
    exosc2 Encodes: [EST] fa97b01, IMAGE:6903240 (1) (order this)
    [cDNA] MGC:110117 (1) (order this), MGC:192005 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017572 (1) 1013 bp
    Genomic GenBank:CU929062 (1) 111698 bp
    Select Tool
    Polypeptide UniProtKB:F8W3K6 (1) 295 aa
    Sequence Clusters UniGene:76338 (1)
    Sequence Information (all 19)
    ORTHOLOGY for exosc2 ( Chr: 5 )
    CITATIONS (18)