Gene

exosc2

ID
ZDB-GENE-050417-27
Name
exosome component 2
Symbol
exosc2 Nomenclature History
Previous Names
  • fa97b01
  • wu:fa97b01
  • zgc:110117
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Predicted to be involved in RNA metabolic process. Predicted to localize to cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in immature eye; midbrain hindbrain boundary; and optic tectum. Orthologous to human EXOSC2 (exosome component 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Yatsuka et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With exosc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
short stature, hearing loss, retinitis pigmentosa, and distinctive facies Alliance Short stature, hearing loss, retinitis pigmentosa, and distinctive facies 617763
Associated With exosc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004088 K Homology domain, type 1
Domain IPR025721 Exosome complex component, N-terminal domain
Family IPR026699 Exosome complex RNA-binding protein 1/RRP40/RRP4
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR036612 K Homology domain, type 1 superfamily
Domain Details Per Protein
Protein Length Exosome complex component, N-terminal domain Exosome complex RNA-binding protein 1/RRP40/RRP4 K Homology domain, type 1 K Homology domain, type 1 superfamily Nucleic acid-binding, OB-fold
UniProtKB:F8W3K6 295
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations