ZFIN ID: ZDB-GENE-050417-267
Gene Name: actin, alpha 1a, skeletal muscle
Gene Symbol: acta1a
Previous Names: hm:zeh0293, zeh0293, zgc:112098
Location: Chr: 1 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 4 publications
Directly Submitted Expression Data: 6 figures (12 images) from Rauch et al., 2003 [fb19e10]
  6 figures (17 images) from Thisse et al., 2004 [MGC:112098]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  adaxial cell, brain, fast muscle cell striated muscle thin filament, fin (all 12) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH acta1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital fiber-type disproportion Myopathy, congenital, with fiber-type disproportion 1 255310
nemaline myopathy Myopathy, actin, congenital, with cores 161800
Myopathy, actin, congenital, with excess of thin myofilaments 161800
Nemaline myopathy 3, autosomal dominant or recessive 161800
GENE ONTOLOGY
Ontology GO Term
Biological Process mesenchyme migration (more)
Cellular Component cell body (more)
Molecular Function ATP binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004000 (1)
  • InterPro:IPR004001 (1)
  • InterPro:IPR020902 (1)
  • PROSITE:PS00406 (1)
  • PROSITE:PS00432 (1)
  • PROSITE:PS01132 (1)
  • Pfam:PF00022 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acta1a-001 (1) 1612
    ncRNA acta1a-002 (1) 557
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acta1a
    Tg(acta1a:stac3-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acta1aContained in: [BAC] CH211-133L11 (1) (order this)
    acta1aEncodes: [EST] fb19e10 (1) (order this), zeh0293
    [cDNA] MGC:112098 (1) (order this), MGC:191650 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017750 (1) 1600bp
    Genomic GenBank:AL929114 (1) 180158bp
    Select Tool
    Polypeptide UniProtKB:F1QUN8 (1) 377aa
    Sequence Clusters UniGene:75118 (1)
    Sequence Information (all 15)
    OTHER acta1a GENE PAGES
  • Gene:550445 (1)
  • VEGA:OTTDARG00000021882 (1)
  • Ensembl(GRCz10):ENSDARG00000036371 (1)
  • ORTHOLOGY for acta1a (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human ACTA1 1
  • Gene:58
  • OMIM:102610
  • HGNC:129
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Acta1 8
  • MGI:87902
  • Gene:11459
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (25)