ZFIN ID: ZDB-GENE-050417-267
Gene Name: actin, alpha 1a, skeletal muscle
Gene Symbol: acta1a

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: hm:zeh0293, zeh0293, zgc:112098

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 4 publications
Directly Submitted Expression Data: 6 figures (12 images) from Rauch et al., 2003 [fb19e10]
  6 figures (17 images) from Thisse et al., 2004 [MGC:112098]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  adaxial cell, brain, fast muscle cell striated muscle thin filament, fin (all 12) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9336 Point Mutation Unknown Premature Stop ENU
sa18713 Point Mutation Unknown Premature Stop ENU
sa19610 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acta1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital fiber-type disproportion Myopathy, congenital, with fiber-type disproportion 1 255310
    nemaline myopathy Myopathy, actin, congenital, with cores 161800
    Myopathy, actin, congenital, with excess of thin myofilaments 161800
    Nemaline myopathy 3, autosomal dominant or recessive 161800
    ?Myopathy, scapulohumeroperoneal 616852
    ?Myopathy, scapulohumeroperoneal 616852
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mesenchyme migration (more)
    Cellular Component cell body (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004000 (1)
  • InterPro:IPR004001 (1)
  • InterPro:IPR020902 (1)
  • PROSITE:PS00406 (1)
  • PROSITE:PS00432 (1)
  • PROSITE:PS01132 (1)
  • Pfam:PF00022 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acta1a-001 (1) 1612
    ncRNA acta1a-002 (1) 557
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acta1a
    Tg(acta1a:stac3-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acta1aContained in: [BAC] CH211-133L11 (1) (order this)
    acta1aEncodes: [EST] fb19e10 (1) (order this), zeh0293
    [cDNA] MGC:112098 (1) (order this), MGC:191650 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017750 (1) 1600bp
    Genomic GenBank:AL929114 (1) 180158bp
    Select Tool
    Polypeptide UniProtKB:F1QUN8 (1) 377aa
    Sequence Clusters UniGene:75118 (1)
    Sequence Information (all 15)
    OTHER acta1a GENE PAGES
  • Gene:550445 (1)
  • VEGA:OTTDARG00000021882 (1)
  • Ensembl(GRCz10):ENSDARG00000036371 (1)
  • ORTHOLOGY for acta1a (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human ACTA1 1
  • Gene:58
  • OMIM:102610
  • HGNC:129
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Acta1 8
  • MGI:87902
  • Gene:11459
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (27)