Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050417-267
Gene Name: actin, alpha 1a, skeletal muscle
Gene Symbol: acta1a
Previous Names: hm:zeh0293, zeh0293, zgc:112098
Location: Chr: 1   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 3 publications
Directly Submitted Expression Data: 6 figures (12 images) from Rauch et al., 2003 [fb19e10]
  6 figures (17 images) from Thisse et al., 2004 [MGC:112098]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  adaxial cell, brain, fin, heart (all 10) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Myopathy, actin, congenital, with cores 161800
Myopathy, actin, congenital, with excess of thin myofilaments 161800
Myopathy, congenital, with fiber-type disproportion 1 255310
Nemaline myopathy 3, autosomal dominant or recessive 161800
GENE ONTOLOGY
Ontology GO Term
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004000 (1)
  • InterPro:IPR004001 (1)
  • InterPro:IPR020902 (1)
  • PROSITE:PS00406 (1)
  • PROSITE:PS00432 (1)
  • PROSITE:PS01132 (1)
  • Pfam:PF00022 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acta1a-001 (1) 1612
    ncRNA acta1a-002 (1) 557
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acta1a
    Tg(acta1a:stac3-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acta1a Contained in: [BAC] CH211-133L11 (1) (order this)
    acta1a Encodes: [EST] fb19e10 (1), zeh0293
    [cDNA] MGC:112098 (1) (order this), MGC:191650 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017750 (1) 1600 bp
    Genomic GenBank:AL929114 (1) 180158 bp
    Select Tool
    Polypeptide UniProtKB:F1QUN8 (1) 377 aa
    Sequence Clusters UniGene:75118 (1)
    Sequence Information (all 15)
    OTHER acta1a GENE PAGES
  • Gene:550445 (1)
  • VEGA:OTTDARG00000021882 (1)
  • Ensembl(Zv9):ENSDARG00000036371 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish acta1a 1  
    Human ACTA1 1 (1q42.13)
  • OMIM:102610
  • Gene:58
  • Mouse Acta1 8 ( 72.26 cM)
  • MGI:87902
  • Gene:11459
  • Orthology Details
    CITATIONS (18)