slc27a4

ID

ZDB-GENE-050417-248

Name

solute carrier family 27 member 4

Symbol

slc27a4 Nomenclature History

Previous Names

fatp4 (1)
sb:eu977
zgc:112138

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable long-chain fatty acid transmembrane transporter activity and oleoyl-CoA ligase activity. Predicted to be involved in long-chain fatty acid import into cell; long-chain fatty acid metabolic process; and medium-chain fatty acid transport. Predicted to act upstream of or within lipid metabolic process. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Is expressed in intestinal bulb and intestine. Orthologous to human SLC27A4 (solute carrier family 27 member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu977 (3 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc27a4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Ichthyosis prematurity syndrome	608649

Associated With slc27a4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020845	AMP-binding, conserved site
Conserved_site	IPR022272	Lipocalin family conserved site
Domain	IPR000873	AMP-dependent synthetase/ligase domain
Domain	IPR025110	AMP-binding enzyme, C-terminal domain
Homologous_superfamily	IPR042099	ANL, N-terminal domain
Homologous_superfamily	IPR045851	AMP-binding enzyme, C-terminal domain superfamily