ZFIN ID: ZDB-GENE-050417-242
Gene Name: claudin 19
Gene Symbol: cldn19    Nomenclature History

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Previous Name: zgc:112141

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to localize to bicellular tight junction and plasma membrane. Human ortholog(s) of this gene implicated in renal hypomagnesemia 5 with ocular involvement. Orthologous to human CLDN19 (claudin 19).
Genome Resources: Alliance (1),  Gene:550431 (1),  Ensembl(GRCz11):ENSDARG00000044569 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21966 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cldn19 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    renal hypomagnesemia 5 with ocular involvement Alliance Hypomagnesemia 5, renal, with ocular involvement 248190
    DISEASE ASSOCIATED WITH cldn19 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process bicellular tight junction assembly (more)
    Cellular Component bicellular tight junction (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cldn19-201 (1)    Ensembl 1457
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cldn19 No data available
    MARKER RELATIONSHIPS
    cldn19 Contained in: [Fosmid] CH1073-250I23 (1), ZFOS-1388F10 (1)
    cldn19 Encodes: [cDNA] MGC:112141 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001017736 (1) 1461 nt
    Genomic GenBank:FO704596 (1) 38521 nt
    Select Tool
    Polypeptide UniProtKB:Q567D5 (1) 209 aa
    Sequence Information (all 17)
    ORTHOLOGY for cldn19 ( Chr: 11 )
    CITATIONS (23)