Gene
agr2
- ID
- ZDB-GENE-050417-214
- Name
- anterior gradient 2
- Symbol
- agr2 Nomenclature History
- Previous Names
-
- sb:eu228
- wu:fj29g05
- zgc:112187
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have protein homodimerization activity. Involved in intestinal epithelial cell differentiation. Predicted to localize to endoplasmic reticulum and extracellular region. Is expressed in several structures, including digestive system; hatching gland; integument; olfactory system; and vestibuloauditory system. Human ortholog(s) of this gene implicated in in situ carcinoma. Orthologous to several human genes including AGR2 (anterior gradient 2, protein disulphide isomerase family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 44 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu228 (13 images)
- IMAGE:7163877 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Chen et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Respiratory infections, recurrent, and failure to thrive with or without diarrhea | 620233 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Thioredoxin-like superfamily |
|---|---|---|
|
UniProtKB:Q5RZ65
|
171 |
Interactions and Pathways
No data available
Plasmids
No data available