Gene

mrpl12

ID
ZDB-GENE-050417-187
Name
mitochondrial ribosomal protein L12
Symbol
mrpl12 Nomenclature History
Previous Names
  • im:6893415
  • zgc:112445
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial transcription. Predicted to localize to mitochondrial large ribosomal subunit. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and pectoral fin. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human MRPL12 (mitochondrial ribosomal protein L12).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mrpl12 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 45 Alliance ?Combined oxidative phosphorylation deficiency 45 618951
Associated With mrpl12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008932 Ribosomal protein L7/L12, oligomerisation
Domain IPR013823 Ribosomal protein L7/L12, C-terminal
Family IPR000206 Ribosomal protein L7/L12
Homologous_superfamily IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like
Homologous_superfamily IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily
Domain Details Per Protein
Protein Length Ribosomal protein L7/L12 Ribosomal protein L7/L12, C-terminal Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Ribosomal protein L7/L12, oligomerisation Ribosomal protein L7/L12, oligomerisation domain superfamily
UniProtKB:Q566V8 194
UniProtKB:X1WHQ5 199
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations