ZFIN Gene: sema6dl

ZFIN ID: ZDB-GENE-050417-171

ZFIN ID: ZDB-GENE-050417-171

Gene Name:

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like

Gene Symbol:

sema6dl

Sequence Ontology ID :

SO:0000704

Previous Names:

si:ch211-278n20.1, zgc:112012 (1)

Location:

Chr: 18 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon ...

GENE EXPRESSION
All Expression Data:	9 figures from 3 publications
Directly Submitted Expression Data:	6 figures (20 images) from Thisse et al., 2004 [MGC:112012]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
	alar plate midbrain region basal plate midbrain region caudal tuberculum cranial ganglion diencephalon fin bud forebrain hindbrain lateral forebrain bundle lens margin medulla oblongata midbrain midbrain neural keel myotome neural plate optic tectum otic region otic vesicle pharyngeal arch retinal ganglion cell rhombomere solid lens vesicle somite tegmentum telencephalon thalamus vagal ganglion whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa8429	Point Mutation	Unknown	Missense, Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa43158	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa45647	Point Mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH sema6dl HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH sema6dl VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	negative chemotaxis (more)
Cellular Component	integral component of membrane (more)
Molecular Function	chemorepellent activity (more)

GO Terms (all 11)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001627 (1) InterPro:IPR002165 (1) InterPro:IPR015943 (1) InterPro:IPR027231 (1) InterPro:IPR036352 (1)	PROSITE:PS51004 (1)	Pfam:PF01403 (1) Pfam:PF01437 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	sema6dl-203 (1)	3000	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	sema6dl-204 (1)	3057	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	sema6dl-205 (1)	540	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM sema6dl No data available

MARKER RELATIONSHIPS

sema6dlContained in:	[BAC] CH211-278N20 (1) (order this)
sema6dlEncodes:	[cDNA] cssl:d408 (1), cssl:d410 (1), MGC:112012 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001017682 (1)	3157bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX323575 (1)	151144bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A3KPS3 (1)	1018aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:124085 (1)

Sequence Information (all 40)

OTHER sema6dl GENE PAGES

Alliance (1)

Gene:550377 (1)

VEGA:OTTDARG00000013373 (1)

Ensembl(GRCz11):ENSDARG00000011533 (2)

ORTHOLOGY for sema6dl (Chr: 18)

CITATIONS (21)

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