ZFIN Gene: sema6dl

ZFIN ID: ZDB-GENE-050417-171

ZFIN ID: ZDB-GENE-050417-171

Gene Name:

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like

Gene Symbol:

sema6dl Nomenclature History

Previous Names:

si:ch211-278n20.1, zgc:112012 (1)

Gene Type:

protein_coding_gene

Location:

Chr: 18 Mapping Details/Browsers

Description:

Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including generation of neurons; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in several structures, including brain; cranial ganglion; head; midbrain neural keel; and midbrain neural tube. Orthologous to human SEMA6D (semaphorin 6D).

Genome Resources:

Alliance (1), Gene:550377 (1), Ensembl(GRCz11):ENSDARG00000011533 (2)

GENE EXPRESSION
All Expression Data:	9 figures from 3 publications
Directly Submitted Expression Data:	6 figures (20 images) from Thisse et al., 2004 [MGC:112012]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
	alar plate midbrain region basal plate midbrain region caudal tuberculum cranial ganglion diencephalon fin bud forebrain hindbrain lateral forebrain bundle lens margin medulla oblongata midbrain midbrain neural keel myotome neural plate optic tectum otic region otic vesicle pharyngeal arch retinal ganglion cell rhombomere solid lens vesicle somite tegmentum telencephalon thalamus vagal ganglion whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa8429	Point Mutation	Unknown	Missense, Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa43158	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa45647	Point Mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH sema6dl HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH sema6dl VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	axon guidance (more)
Cellular Component	integral component of membrane (more)
Molecular Function	semaphorin receptor binding (more)

GO Terms (all 12)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	sema6dl-203 (1)	3000	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	sema6dl-204 (1)	3057	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	sema6dl-205 (1)	540	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: UCSC, NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM sema6dl No data available

MARKER RELATIONSHIPS

sema6dl Contained in:	[BAC] CH211-278N20 (1)
sema6dl Encodes:	[cDNA] cssl:d408 (1), cssl:d410 (1), MGC:112012 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001017682 (1)	3157 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX323575 (1)	151144 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A3KPS3 (1)	1018 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 39)

ORTHOLOGY for sema6dl ( Chr: 18 )

CITATIONS (23)

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