ZFIN ID: ZDB-GENE-050417-107
Gene Name: zgc:110239
Gene Symbol: zgc:110239    Nomenclature History

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Previous Names: fi12h07, wu:fi12h07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to localize to the extracellular space and lysosome. Is expressed in several structures, including optic vesicle; pigment cell; retina; vasculature; and yolk syncytial layer.
Genome Resources: Alliance (1),  Gene:550326 (1),  Ensembl(GRCz11):ENSDARG00000077664 (2)

Nomenclature Note: This gene is characterized by full length cDNAs isolated as part of the Zebrafish Gene Collection (ZGC). When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix `zgc:' indicates that this gene is represented by cDNAs generated by the ZGC project.

GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (14 images) from Thisse et al., 2004 [MGC:110239]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3004 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH zgc:110239 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH zgc:110239 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component extracellular space (more)
Molecular Function cysteine-type peptidase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Domain IPR000668 Peptidase C1A, papain C-terminal
Domain IPR013201 Cathepsin propeptide inhibitor domain (I29)
Active_site IPR025660 Cysteine peptidase, histidine active site
Active_site IPR025661 Cysteine peptidase, asparagine active site
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain IPR039417 Papain-like cysteine endopeptidase
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA zgc:110239-201 (1)    Ensembl 1963
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM zgc:110239 No data available
MARKER RELATIONSHIPS
zgc:110239 Contained in: [BAC] DKEY-166K12 (1) (order this)
zgc:110239 Contains: [SNP] rs3728991 (1)
zgc:110239 Encodes: [EST] fi12h07
[cDNA] MGC:110239 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001017633 (1) 1928 bp
Genomic GenBank:BX950855 (1) 78444 bp
Select Tool
Polypeptide UniProtKB:F1R9W6 (1) 546 aa
Sequence Information (all 17)
ORTHOLOGY for zgc:110239 ( Chr: 19 )
CITATIONS (19)