Gene

st3gal3b

ID
ZDB-GENE-050411-13
Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
Symbol
st3gal3b Nomenclature History
Previous Names
  • SIAT6 (1)
  • st3gal3-r1 (1)
  • st3gal3l
  • im:6892850
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have N-acetyllactosaminide alpha-2,3-sialyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to localize to Golgi apparatus and integral component of membrane. Is expressed in several structures, including cardiovascular system; corpuscles of Stannius; hypochord; pleuroperitoneal region; and ventral mesoderm. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and developmental and epileptic encephalopathy 15. Orthologous to human ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With st3gal3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive non-syndromic intellectual disability Alliance Intellectual developmental disorder, autosomal recessive 12 611090
developmental and epileptic encephalopathy 15 Alliance Developmental and epileptic encephalopathy 15 615006
Associated With st3gal3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001675 Glycosyl transferase family 29
Family IPR012163 Sialyltransferase
Homologous_superfamily IPR038578 GT29-like superfamiliy
Domain Details Per Protein
Protein Length Glycosyl transferase family 29 GT29-like superfamiliy Sialyltransferase
UniProtKB:E9QCX5 238
UniProtKB:Q702R8 355
UniProtKB:E7FBG1 356
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations