ZFIN ID: ZDB-GENE-050410-6
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Gene Symbol: abcb8    Nomenclature History

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Previous Name: zgc:113037

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to mitochondrial ATP-gated potassium channel complex. Is expressed in female organism. Orthologous to human ABCB8 (ATP binding cassette subfamily B member 8).
Genome Resources: Alliance (1),  Gene:548340 (1),  Ensembl(GRCz11):ENSDARG00000056672 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113037]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7155111]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32493 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37928 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abcb8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH abcb8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process potassium ion transmembrane transport (more)
    Cellular Component mitochondrial ATP-gated potassium channel complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abcb8-201 (1)    Ensembl 2628
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcb8 No data available
    MARKER RELATIONSHIPS
    abcb8 Contained in: [BAC] DKEYP-87A6 (1)
    abcb8 Encodes: [EST] IMAGE:7155111 (1)
    [cDNA] MGC:113037 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001017544 (1)
    Genomic GenBank:CU019563 (1) 194521 nt
    Select Tool
    Polypeptide UniProtKB:Q56A55 (1) 714 aa
    Sequence Information (all 10)
    ORTHOLOGY for abcb8 ( Chr: 24 )
    CITATIONS (31)