ZFIN ID: ZDB-GENE-050410-16
Gene Name: retinal pigment epithelium-specific protein 65b
Gene Symbol: rpe65b
Previous Names: rpepb (1), 13cIMH (1), si:ch211-198n5.5, wu:fc74c09, zgc:110538
Location: Chr: 8   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
  brain, eye, medial longitudinal fasciculus, optic tectum (all 9) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa21239, sa21240
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Leber congenital amaurosis 2 204100
Retinitis pigmentosa 20 613794
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component cytoplasm (more)
Molecular Function hydrolase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004294 (1)
  • Pfam:PF03055 (1)
  • EC:3.1.1.90 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rpe65b-001 (1) 1945
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rpe65b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rpe65b Contained in: [BAC] CH211-198N5 (1) (order this)
    rpe65b Encodes: [EST] fc74c09
    [cDNA] MGC:110538 (1) (order this), MGC:162449 (1) (order this), MGC:174561 (1) (order this), MGC:191430 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089433 (1) 1949 bp
    Genomic GenBank:CR759968 (1) 182233 bp
    Select Tool
    Polypeptide UniProtKB:A9C3R9 (1) 532 aa
    Sequence Clusters UniGene:79444 (1)
    Sequence Information (all 27)
    OTHER rpe65b GENE PAGES
  • Gene:100002865 (1)
  • VEGA:OTTDARG00000022134 (1)
  • Ensembl(Zv9):ENSDARG00000094752 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish rpe65b 8  
    Human RPE65 1 (1p31)
  • OMIM:180069
  • Gene:6121
  • Mouse Rpe65 3 ( 82.52 cM)
  • MGI:98001
  • Gene:19892
  • Orthology Details
    CITATIONS (17)