Gene

pik3c3

ID
ZDB-GENE-050410-13
Name
phosphatidylinositol 3-kinase, catalytic subunit type 3
Symbol
pik3c3 Nomenclature History
Previous Names
  • im:7147158
  • wu:fc13g06
  • wu:fz51e12
  • zgc:112016
  • zgc:113009
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have 1-phosphatidylinositol-3-kinase activity. Predicted to be involved in several processes, including autophagosome assembly; phosphatidylinositol metabolic process; and phosphatidylinositol-mediated signaling. Predicted to localize to several cellular components, including peroxisome; phagophore assembly site; and phosphatidylinositol 3-kinase complex, class III. Used to study inflammatory bowel disease. Orthologous to human PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Zhao et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pik3c3 Human Ortholog
No data available
Associated With pik3c3 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
Domain IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
Domain IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
Domain IPR002420 Phosphatidylinositol 3-kinase, C2 domain
Family IPR008290 Phosphatidylinositol 3-kinase, Vps34 type
Family IPR015433 Phosphatidylinositol kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR036940 Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
Homologous_superfamily IPR042236 Phosphoinositide 3-kinase, accessory (PIK) domain superfamily
Domain Details Per Protein
Protein Length Armadillo-type fold C2 domain superfamily Phosphatidylinositol 3-/4-kinase, catalytic domain Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily Phosphatidylinositol 3/4-kinase, conserved site Phosphatidylinositol 3-kinase, C2 domain Phosphatidylinositol 3-kinase, Vps34 type Phosphatidylinositol kinase Phosphoinositide 3-kinase, accessory (PIK) domain Phosphoinositide 3-kinase, accessory (PIK) domain superfamily Protein kinase-like domain superfamily
UniProtKB:F8W4V1 726
UniProtKB:Q56A49 372
UniProtKB:Q502M1 726
UniProtKB:F1Q9F3 878
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations