Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050407-2
Gene Name: prostaglandin E synthase
Gene Symbol: ptges
Previous Names: mPGES (1), zgc:110052
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2004 [MGC:110052]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  epidermis, pectoral fin, periderm, splanchnocranium (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa20467
Knockdown reagents: MO1-ptges (1), MO2-ptges (1)
PHENOTYPE
Data: 2 figures from Cha et al., 2006
Observed in: axis, convergent extension involved in gastrulation, epiboly involved in gastrulation with mouth forming second, head (all 6) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process cell migration involved in gastrulation (more)
Molecular Function prostaglandin-E synthase activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001129 (1)
  • InterPro:IPR023352 (1)
  • Pfam:PF01124 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptges-001 (1) 996
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ptges No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ptges Contained in: [BAC] CH211-182D3 (1) (order this), DKEY-125I20 (1)
    ptges Encodes: [cDNA] MGC:110052 (1) (order this), MGC:192121 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001014828 (1) 1001 bp
    Genomic GenBank:BX927184 (1) 160345 bp
    Select Tool
    Polypeptide UniProtKB:Q5IHX7 (1) 146 aa
    Sequence Clusters UniGene:37924 (1)
    Sequence Information (all 16)
    OTHER ptges GENE PAGES
  • Gene:544666 (1)
  • VEGA:OTTDARG00000035252 (1)
  • Ensembl(Zv9):ENSDARG00000020136 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ptges 5  
    Human PTGES 9 (9q34.3)
  • OMIM:605172
  • Gene:9536
  • Orthology Details
    CITATIONS (24)