ZFIN ID: ZDB-GENE-050407-2
Gene Name: prostaglandin E synthase
Gene Symbol: ptges
Previous Names: mPGES (1), zgc:110052
Location: Chr: 5 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2004 [MGC:110052]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  epidermis, pectoral fin, periderm, splanchnocranium (all 6) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa20467 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-ptges (1), MO2-ptges (1)
    PHENOTYPE
    Data: 2 figures from Cha et al., 2006
    Observed in: axis, convergent extension involved in gastrulation, epiboly involved in gastrulation with mouth forming second, head (all 6) expand
    DISEASE ASSOCIATED WITH ptges HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration involved in gastrulation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function prostaglandin-E synthase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001129 (1)
  • InterPro:IPR023352 (1)
  • Pfam:PF01124 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptges-001 (1) 996
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ptges No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ptgesContained in: [BAC] CH211-182D3 (1) (order this), DKEY-125I20 (1) (order this)
    ptgesEncodes: [cDNA] MGC:110052 (1) (order this), MGC:192121 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001014828 (1) 1001bp
    Genomic GenBank:BX927184 (1) 160345bp
    Select Tool
    Polypeptide UniProtKB:Q5IHX7 (1) 146aa
    Sequence Clusters UniGene:37924 (1)
    Sequence Information (all 16)
    OTHER ptges GENE PAGES
  • Gene:544666 (1)
  • VEGA:OTTDARG00000035252 (1)
  • Ensembl(GRCz10):ENSDARG00000020136 (1)
  • ORTHOLOGY for ptges (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human PTGES 9
  • Gene:9536
  • OMIM:605172
  • HGNC:9599
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (3)
    Download Curated Orthology
    CITATIONS (28)