Gene

kcnab1a

ID
ZDB-GENE-050327-79
Name
potassium voltage-gated channel subfamily A regulatory beta subunit 1a
Symbol
kcnab1a Nomenclature History
Previous Names
  • kcnab1
  • zgc:113627 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in immature eye; myotome; nervous system; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnab1a Human Ortholog
No data available
Associated With kcnab1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023210 NADP-dependent oxidoreductase domain
Family IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related
Family IPR005400 Potassium channel, voltage-dependent, beta subunit, KCNAB1
Family IPR005983 Potassium channel, voltage-dependent, beta subunit, KCNAB
Homologous_superfamily IPR036812 NADP-dependent oxidoreductase domain superfamily
Domain Details Per Protein
Protein Length NADP-dependent oxidoreductase domain NADP-dependent oxidoreductase domain superfamily Potassium channel, voltage-dependent, beta subunit, KCNAB Potassium channel, voltage-dependent, beta subunit, KCNAB1 Potassium channel, voltage-dependent, beta subunit, KCNAB-related
UniProtKB:Q4V9G2 295
UniProtKB:Q58EC4 398
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations