Gene

alpi.1

ID
ZDB-GENE-050327-78
Name
alkaline phosphatase, intestinal, tandem duplicate 1
Symbol
alpi.1 Nomenclature History
Previous Names
  • alpi (1)
  • iap (1)
  • im:7149588
  • si:ch211-262h13.1 (1)
  • wu:fa95f04
  • zgc:110794 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have alkaline phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to localize to anchored component of membrane and plasma membrane. Is expressed in several structures, including floor plate; intestine; median fin fold; periderm; and segmental plate. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to human ALPI (alkaline phosphatase, intestinal).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Bates et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alpi.1 Human Ortholog
No data available
Associated With alpi.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018299 Alkaline phosphatase, active site
Family IPR001952 Alkaline phosphatase
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline phosphatase Alkaline phosphatase, active site Alkaline-phosphatase-like, core domain superfamily
UniProtKB:A0A8M3B5T5 453
UniProtKB:Q58EF1 532
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA alpi.1-201 (1) Ensembl 3,420 nt
mRNA alpi.1-203 (1) Ensembl 808 nt
mRNA alpi.1-204 (1) Ensembl 1,871 nt
ncRNA alpi.1-003 (1) Ensembl 785 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations