ZFIN ID: ZDB-GENE-050327-41
Gene Name: inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Gene Symbol: ippk    Nomenclature History

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Previous Names: ipk1 (1), ipk1l (1), si:dkey-42i9.3, zgc:110769

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Exhibits inositol pentakisphosphate 2-kinase activity. Involved in epithelial cilium movement involved in determination of left/right asymmetry and melanosome transport. Localizes to centrosome and ciliary basal body. Is expressed in axial mesoderm; blastodisc; germ ring; margin; and tail bud. Orthologous to human IPPK (inositol-pentakisphosphate 2-kinase).
Genome Resources: Alliance (1),  Gene:541511 (1),  Ensembl(GRCz11):ENSDARG00000003446 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6894363]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24085 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ippk N/A 5
    DISEASE ASSOCIATED WITH ippk HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ippk VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right symmetry (more)
    Cellular Component centrosome (more)
    Molecular Function inositol pentakisphosphate 2-kinase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ippk-201 (1)    Ensembl 2412
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ippk No data available
    MARKER RELATIONSHIPS
    ippk Contained in: [BAC] DKEY-42I9 (order this)
    ippk Encodes: [EST] IMAGE:6894363 (1)
    [cDNA] MGC:110769 (1), MGC:192840 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001014324 (1) 2420 nt
    Genomic GenBank:BX465868 (1) 222195 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B2GT43 (1) 483 aa
    Sequence Information (all 16)
    ORTHOLOGY for ippk ( Chr: 22 )
    CITATIONS (28)