ZFIN ID: ZDB-GENE-050324-2
Gene Name: Wolf-Hirschhorn syndrome candidate 1-like 1
Gene Symbol: whsc1l1

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017439Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017440Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7336 Point Mutation Unknown Nonsynonymous ENU
    sa11365 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa14276 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16134 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21713 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34885 Point Mutation Unknown Premature Stop ENU
    sa38792 Point Mutation Unknown Splice Site ENU
    sa41639 Point Mutation Unknown Premature Stop ENU
    sa41640 Point Mutation Unknown Premature Stop ENU
    scu2 Indel Unknown Unknown CRISPR
    Targeting reagents: CRISPR1-whsc1l1 (1), MO1-whsc1l1 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH whsc1l1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component nucleus (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA whsc1l1-001 (1) 4396
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM whsc1l1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    whsc1l1Contained in: [BAC] CH73-261P11 (order this), CH211-113D22 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005155322 (1) 7249bp
    Genomic GenBank:BX294119 (1) 167603bp
    Select Tool
    Polypeptide UniProtKB:F1QV68 (1) 1563aa
    Sequence Clusters UniGene:134231 (1)
    Sequence Information (all 24)
    OTHER whsc1l1 GENE PAGES
  • Gene:100006350 (1)
  • VEGA:OTTDARG00000030978 (1)
  • Ensembl(GRCz10):ENSDARG00000062765 (1)
  • ORTHOLOGY for whsc1l1 (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human WHSC1L1 8
  • Gene:54904
  • OMIM:607083
  • HGNC:12767
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Nucleotide sequence comparison (1)
    Mouse Whsc1l1 8
  • MGI:2142581
  • Gene:234135
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)