ZFIN ID: ZDB-GENE-050324-2
Gene Name: Wolf-Hirschhorn syndrome candidate 1-like 1
Gene Symbol: whsc1l1
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la017439Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017440Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11365 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14276 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16134 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa21713 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • scu2 Indel CRISPR
    Targeting reagents: CRISPR1-whsc1l1 (1), MO1-whsc1l1 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH whsc1l1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component nucleus (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • EC:2.1.1.43 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA whsc1l1-001 (1) 4396
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM whsc1l1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    whsc1l1 Contained in: [BAC] CH73-261P11 (order this), CH211-113D22 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005155322 (1) 9562 bp
    Genomic GenBank:BX294119 (1) 167603 bp
    Select Tool
    Polypeptide UniProtKB:F1QV68 (1) 1521 aa
    Sequence Clusters UniGene:134231 (1)
    Sequence Information (all 28)
    OTHER whsc1l1 GENE PAGES
  • Gene:100006350 (1)
  • VEGA:OTTDARG00000030978 (1)
  • Ensembl(Zv9):ENSDARG00000062765 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT CL
    Zebrafish whsc1l1 10  
    Human WHSC1L1 8 (8p11.2)
  • OMIM:607083
  • Gene:54904
  • Mouse Whsc1l1 8 ( 14.17 cM)
  • MGI:2142581
  • Gene:234135
  • Orthology Details
    CITATIONS (21)