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ZIRC
ZFIN ID: ZDB-GENE-050320-97
Gene Name: potassium large conductance calcium-activated channel, subfamily M, beta member 2
Gene Symbol: kcnmb2    Nomenclature History

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Previous Name: zgc:101842

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have calcium-activated potassium channel activity and potassium channel regulator activity. Predicted to be involved in detection of calcium ion. Predicted to localize to the voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in hypertension. Orthologous to several human genes including KCNMB2 (potassium calcium-activated channel subfamily M regulatory beta subunit 2).
Genome Resources: Alliance (1),  Gene:541398 (1),  Ensembl(GRCz11):ENSDARG00000006568 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH kcnmb2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH kcnmb2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process potassium ion transport (more)
Cellular Component integral component of membrane (more)
Molecular Function calcium-activated potassium channel activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003930 (1)
  • InterPro:IPR015382 (1)
  • InterPro:IPR037096 (1)
  • Pfam:PF03185 (1)
  • Pfam:PF09303 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA kcnmb2-201 (1)    Ensembl 1182
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kcnmb2 No data available
    MARKER RELATIONSHIPS
    kcnmb2 Contained in: [BAC] CH211-38M6 (1) (order this)
    kcnmb2 Encodes: [cDNA] MGC:101842 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013525 (1) 1205 bp
    Genomic GenBank:CT027646 (1) 176141 bp
    Select Tool
    Polypeptide UniProtKB:A5WVU1 (1) 232 aa
    Sequence Clusters UniGene:87983 (1)
    Sequence Information (all 10)
    ORTHOLOGY for kcnmb2 ( Chr: 2 )
    CITATIONS (13)