ZFIN ID: ZDB-GENE-050320-104
Gene Name: CDC42 effector protein (Rho GTPase binding) 2
Gene Symbol: cdc42ep2    Nomenclature History

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Previous Name: zgc:103557

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have GTP-Rho binding activity. Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component biogenesis; and regulation of cell shape. Predicted to localize to cytoplasm; cytoskeleton; and plasma membrane. Is expressed in nervous system; optic vesicle; and presumptive neural retina. Orthologous to human CDC42EP2 (CDC42 effector protein 2).
Genome Resources: Alliance (1),  Gene:541404 (1),  Ensembl(GRCz11):ENSDARG00000053959 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [IMAGE:7162804]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45214 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cdc42ep2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdc42ep2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of actin filament polymerization (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTP-Rho binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cdc42ep2-201 (1)    Ensembl 1481
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdc42ep2 No data available
    MARKER RELATIONSHIPS
    cdc42ep2 Contained in: [BAC] DKEY-99P10 (1) (order this)
    cdc42ep2 Encodes: [EST] IMAGE:7162804 (1)
    [cDNA] MGC:103557 (1), MGC:192526 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013531 (1) 1523 nt
    Genomic GenBank:CT025939 (1) 56634 nt
    Select Tool
    Polypeptide UniProtKB:Q5BKX1 (1) 247 aa
    Sequence Information (all 20)
    ORTHOLOGY for cdc42ep2 ( Chr: 5 )
    CITATIONS (19)