ZFIN ID: ZDB-GENE-050320-10
Gene Name: mitogen-activated protein kinase 7
Gene Symbol: mapk7    Nomenclature History

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Previous Names: ERK5 (1), fb73b02, wu:fb73b02, zgc:113111

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have MAP kinase activity. Involved in ossification. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including brain; head; notochord; pronephric duct; and tail bud. Orthologous to human MAPK7 (mitogen-activated protein kinase 7).
Genome Resources: Alliance (1),  Gene:541323 (1),  Ensembl(GRCz11):ENSDARG00000023110 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6902169]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35192 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-mapk7
    1
    MO1-mapk7 N/A 1
    PHENOTYPE
    Data: 2 figures from Zhou et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH mapk7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mapk7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ossification (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mapk7-202 (1)    Ensembl 3968
    mapk7-203 (1)    Ensembl 3295
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mapk7 No data available
    MARKER RELATIONSHIPS
    mapk7 Contained in: [BAC] DKEY-32N7 (1) (order this)
    mapk7 Encodes: [EST] fb73b02, IMAGE:6902169 (1)
    [cDNA] MGC:113111 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013451 (1) 2589 nt
    Genomic GenBank:AL954132 (1) 197745 nt
    Select Tool
    Polypeptide UniProtKB:E9QEY0 (1) 1080 aa
    Sequence Information (all 15)
    ORTHOLOGY for mapk7 ( Chr: 12 )
    CITATIONS (25)