ZFIN ID: ZDB-GENE-050318-2
Gene Name: lectin, galactoside-binding, soluble, 2a
Gene Symbol: lgals2a    Nomenclature History

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Previous Names: Drgal1-L2 (1), lgals1l2, zgc:86752

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Exhibits galactoside binding activity and laminin binding activity. Involved in several processes, including positive regulation of wound healing; skeletal muscle fiber development; and sprouting angiogenesis. Predicted to localize to extracellular space. Is expressed in digestive system; musculature system; nervous system; notochord; and spleen. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human LGALS2 (galectin 2).
Genome Resources: Alliance (1),  Gene:405830 (1),  Ensembl(GRCz11):ENSDARG00000054942 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024084Tg Transgenic Insertion Unknown Unknown DNA
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-lgals2a N/A 1
MO2-lgals2a N/A 1
MO3-lgals2a N/A 1
MO4-lgals2a N/A 1
DISEASE ASSOCIATED WITH lgals2a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Myocardial infarction, susceptibility to} 608446
DISEASE ASSOCIATED WITH lgals2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sprouting angiogenesis (more)
Cellular Component extracellular space (more)
Molecular Function galactoside binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lgals2a-202 (1)    Ensembl 883
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lgals2a No data available
MARKER RELATIONSHIPS
lgals2a Contained in: [BAC] DKEYP-51A2 (1)
lgals2a Encodes: [cDNA] MGC:86752 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_212894 (1) 850 nt
Genomic GenBank:BX908785 (1) 68916 nt
Select Tool
Polypeptide UniProtKB:Q6IQI2 (1) 134 aa
Sequence Information (all 15)
ORTHOLOGY for lgals2a ( Chr: 3 )
CITATIONS (31)