ZFIN ID: ZDB-GENE-050311-6
Gene Name: vasoactive intestinal peptide receptor 1b
Gene Symbol: vipr1b    Nomenclature History

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Previous Names: vipr1, VPAC1 (1), vpac1 receptor (1), VPAC1R (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have G protein-coupled peptide receptor activity and peptide hormone binding activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in achalasia. Is expressed in several structures, including eye; gut; heart; integument; and pleuroperitoneal region. Orthologous to human VIPR1 (vasoactive intestinal peptide receptor 1).
Genome Resources: Alliance (1),  Gene:503868 (1),  Ensembl(GRCz11):ENSDARG00000059058 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014535Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39446 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45828 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vipr1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vipr1b VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR017983 GPCR, family 2, secretin-like, conserved site
    Domain IPR001879 GPCR, family 2, extracellular hormone receptor domain
    Domain IPR017981 GPCR, family 2-like
    Family IPR000832 GPCR, family 2, secretin-like
    Family IPR001771 GPCR, family 2, vasoactive intestinal peptide receptor 1
    Homologous_superfamily IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vipr1b-201 (1)    Ensembl 1741
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vipr1b No data available
    MARKER RELATIONSHIPS
    vipr1b Contained in: [BAC] CH73-389C16 (1), DKEY-191J10 (1) (order this)
    vipr1b Encodes: [cDNA] MGC:194407 (1), MGC:194416 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013353 (1) 1668 nt
    Genomic GenBank:CR931724 (1) 130017 nt
    Select Tool
    Polypeptide UniProtKB:F1R383 (1) 446 aa
    Sequence Information (all 21)
    ORTHOLOGY for vipr1b ( Chr: 24 )
    CITATIONS (31)