Gene

btc

ID
ZDB-GENE-050311-1
Name
betacellulin, epidermal growth factor family member
Symbol
btc Nomenclature History
Previous Names
  • zgc:153253
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of epidermal growth factor-activated receptor activity; and positive regulation of mitotic nuclear division. Predicted to localize to extracellular space. Is expressed in heart and retina. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human BTC (betacellulin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With btc Human Ortholog
No data available
Associated With btc Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Family IPR015497 Epidermal growth factor receptor ligand
Domain Details Per Protein
Protein Length EGF-like domain Epidermal growth factor receptor ligand
UniProtKB:A0A0R4INZ6 178
UniProtKB:A4QNZ3 178
UniProtKB:Q1LVQ0 178
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations