ZFIN ID: ZDB-GENE-050310-7
Gene Name: Down syndrome cell adhesion molecule a
Gene Symbol: dscama    Nomenclature History

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Previous Names: dscam, zDscam (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have cell-cell adhesion mediator activity. Involved in cell migration involved in gastrulation. Localizes to integral component of plasma membrane. Is expressed in nervous system. Orthologous to human DSCAM (DS cell adhesion molecule).
Genome Resources: Alliance (1),  Gene:568643 (1),  Ensembl(GRCz11):ENSDARG00000024865 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7221 Point Mutation Unknown Splice Site ENU
sa11007 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11753 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18994 Point Mutation Unknown Splice Site ENU
    sa21791 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21792 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21793 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31795 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41717 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41718 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41719 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-dscama
    2
    CRISPR2-dscama
    1
    MO1-dscama N/A 2
    MO2-dscama N/A 1
    MO3-dscama N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dscama HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dscama VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration involved in gastrulation (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function cell-cell adhesion mediator activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dscama-202 (1)    Ensembl 6036
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dscama No data available
    MARKER RELATIONSHIPS
    dscama Contained in: [BAC] CH211-231M12, CH211-284B10
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030224 (1) 6659 nt
    Genomic GenBank:BX248386 (1) 148681 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QL08 (1) 2036 aa
    Sequence Information (all 24)
    ORTHOLOGY for dscama ( Chr: 10 )
    CITATIONS (24)