Gene

pik3r4

ID
ZDB-GENE-050309-84
Name
phosphoinositide-3-kinase, regulatory subunit 4
Symbol
pik3r4 Nomenclature History
Previous Names
  • im:7148788
  • vps15 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including autophagy of peroxisome; late endosome to vacuole transport; and protein targeting to vacuole. Predicted to localize to late endosome; nucleus-vacuole junction; and phosphatidylinositol 3-kinase complex, class III. Is expressed in head and pronephric duct. Orthologous to human PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Stoetzel et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pik3r4 Human Ortholog
No data available
Associated With pik3r4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR000719 Protein kinase domain
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR021133 HEAT, type 2
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold HEAT, type 2 Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E7FAU9 1347
UniProtKB:E9QFS6 1340
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations