Gene

pnpla7b

ID

ZDB-GENE-050309-66

Name

patatin-like phospholipase domain containing 7b

Symbol

pnpla7b Nomenclature History

Previous Names

pnpla7
im:7148262 (1)
si:dkey-16g11.3

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable lysophospholipase activity. Predicted to act upstream of or within lipid catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human PNPLA7 (patatin like phospholipase domain containing 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7148262 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pnpla7b Human Ortholog

No data available

Associated With pnpla7b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000595	Cyclic nucleotide-binding domain
Domain	IPR002641	Patatin-like phospholipase domain
Family	IPR050301	Neuropathy target esterase
Homologous_superfamily	IPR014710	RmlC-like jelly roll fold
Homologous_superfamily	IPR016035	Acyl transferase/acyl hydrolase/lysophospholipase
Homologous_superfamily	IPR018490	Cyclic nucleotide-binding domain superfamily

Domain Details Per Protein

Protein	Length	Acyl transferase/acyl hydrolase/lysophospholipase	Cyclic nucleotide-binding domain	Cyclic nucleotide-binding domain superfamily	Neuropathy target esterase	Patatin-like phospholipase domain	RmlC-like jelly roll fold
UniProtKB:A0A8M2BCG5 InterPro	968
UniProtKB:A0A8M3B9K8 InterPro	970
UniProtKB:A0A8N7T7U6 InterPro	1340
UniProtKB:A0A8M3ASE2 InterPro	970

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pnpla7b-201 (1) Ensembl	Ensembl	5,811 nt	Select Tool ZFIN BLAST
mRNA	pnpla7b-202 (1) Ensembl	Ensembl	4,547 nt	Select Tool ZFIN BLAST
mRNA	pnpla7b-203 (1) Ensembl	Ensembl	5,892 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations