Gene

kdm7ab

ID
ZDB-GENE-050309-32
Name
lysine (K)-specific demethylase 7Ab
Symbol
kdm7ab Nomenclature History
Previous Names
  • kdm7b (1)
  • im:7141664
  • jhdm1D (1)
  • jhdm1db
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Exhibits histone demethylase activity (H3-K27 specific) and histone demethylase activity (H3-K9 specific). Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and midbrain development. Predicted to localize to nucleus. Is expressed in brain; fin; gill; and tail bud. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kdm7ab Human Ortholog
No data available
Associated With kdm7ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
Domain IPR001965 Zinc finger, PHD-type
Domain IPR003347 JmjC domain
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR041070 Jumonji, helical domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length JmjC domain Jumonji, helical domain Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, PHD-type, conserved site Zinc finger, RING/FYVE/PHD-type
UniProtKB:P0CF52
UniProtKB:X1WCI1 41
UniProtKB:F1QHF6 919
UniProtKB:A0A0R4IPR3 894
UniProtKB:A0A0R4IAC4 394
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations