ZFIN ID: ZDB-GENE-050309-289
Gene Name: SET domain containing 1B, histone lysine methyltransferase a
Gene Symbol: setd1ba    Nomenclature History

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Previous Names: im:7156157, si:dkey-237o15.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and histone-lysine N-methyltransferase activity. Involved in hematopoietic progenitor cell differentiation. Predicted to localize to Set1C/COMPASS complex; chromosome; and nuclear speck. Is expressed in brain; cerebellum; and retinal neural layer. Orthologous to human SETD1B (SET domain containing 1B, histone lysine methyltransferase).
Genome Resources: Alliance (1),  Gene:567970 (1),  Ensembl(GRCz11):ENSDARG00000060847 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 2 figures (3 images) from Thisse et al., 2004 [IMAGE:7156157]
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa714 Point Mutation Unknown Premature Stop ENU
sa12989 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13004 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34982 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-setd1ba
    1
    CRISPR2-setd1ba
    1
    CRISPR3-setd1ba
    1
    CRISPR4-setd1ba
    1
    MO1-setd1ba N/A 1
    MO2-setd1ba N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH setd1ba HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH setd1ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hematopoietic progenitor cell differentiation (more)
    Cellular Component chromosome (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA setd1ba-201 (1)    Ensembl 5953
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM setd1ba No data available
    MARKER RELATIONSHIPS
    setd1ba Contained in: [BAC] CH211-265M20 (1), DKEY-237O15 (1) (order this)
    setd1ba Encodes: [EST] IMAGE:7156157 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045134 (1) 8154 nt
    Genomic GenBank:BX005309 (1) 179240 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IPF5 (1) 1847 aa
    Sequence Information (all 27)
    ORTHOLOGY for setd1ba ( Chr: 10 )
    CITATIONS (25)