Gene

sod3a

ID
ZDB-GENE-050309-208
Name
superoxide dismutase 3, extracellular a
Symbol
sod3a Nomenclature History
Previous Names
  • im:7151832
  • zgc:165473
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sod3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Superoxide dismutase, elevated extracellular]
Associated With sod3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018152 Superoxide dismutase, copper/zinc, binding site
Domain IPR001424 Superoxide dismutase, copper/zinc binding domain
Family IPR024134 Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone
Family IPR024141 Extracellular superoxide dismutase [Cu-Zn]
Homologous_superfamily IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily
Domain Details Per Protein
Protein Length Extracellular superoxide dismutase [Cu-Zn] Superoxide dismutase, copper/zinc binding domain Superoxide dismutase, copper/zinc, binding site Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone Superoxide dismutase-like, copper/zinc binding domain superfamily
UniProtKB:F1R0Y7 213
UniProtKB:A5PLA4 213
UniProtKB:H9L6X3 213
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations