ZFIN ID: ZDB-GENE-050309-170
Gene Name: adenylate kinase 7b
Gene Symbol: ak7b    Nomenclature History

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Previous Names: im:7150989, zgc:165635

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have adenylate kinase activity; cytidylate kinase activity; and nucleoside diphosphate kinase activity. Predicted to be involved in nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process; and purine nucleotide metabolic process. Predicted to localize to cytoplasm. Is expressed in nervous system; neural tube; and pronephric duct. Human ortholog(s) of this gene implicated in male infertility. Orthologous to human AK7 (adenylate kinase 7).
Genome Resources: Alliance (1),  Gene:504040 (1),  Ensembl(GRCz11):ENSDARG00000017023 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23041 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ak7b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Spermatogenic failure 27 617965
    DISEASE ASSOCIATED WITH ak7b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process nucleobase-containing compound metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function adenylate kinase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ak7b-201 (1)    Ensembl 2453
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ak7b No data available
    MARKER RELATIONSHIPS
    ak7b Contained in: [BAC] DKEY-288A3 (1) (order this)
    ak7b Encodes: [EST] IMAGE:7150989 (1)
    [cDNA] MGC:165635 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001109698 (1) 2468 nt
    Genomic GenBank:CU571402 (1) 155030 nt
    Select Tool
    Polypeptide UniProtKB:A7MD66 (1) 699 aa
    Sequence Information (all 14)
    ORTHOLOGY for ak7b ( Chr: 17 )
    CITATIONS (19)