Gene

ak7b

ID
ZDB-GENE-050309-170
Name
adenylate kinase 7b
Symbol
ak7b Nomenclature History
Previous Names
  • im:7150989
  • zgc:165635
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have adenylate kinase activity; cytidylate kinase activity; and nucleoside diphosphate kinase activity. Predicted to be involved in nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process; and purine nucleotide metabolic process. Predicted to localize to cytoplasm. Is expressed in nervous system; neural tube; and pronephric duct. Human ortholog(s) of this gene implicated in spermatogenic failure 27. Orthologous to human AK7 (adenylate kinase 7).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ak7b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spermatogenic failure 27 Alliance ?Spermatogenic failure 27 617965
Associated With ak7b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR007858 Dpy-30 motif
Family IPR000850 Adenylate kinase/UMP-CMP kinase
Family IPR026867 Adenylate kinase 7
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length Adenylate kinase 7 Adenylate kinase/UMP-CMP kinase Dpy-30 motif NAD(P)-binding domain superfamily P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q58EE2 387
UniProtKB:A7MD66 699
UniProtKB:F1QF80 699
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations