Gene

ppm1kb

ID
ZDB-GENE-050306-8
Name
protein phosphatase, Mg2+/Mn2+ dependent 1Kb
Symbol
ppm1kb Nomenclature History
Previous Names
  • pp2cm (1)
  • ppm1k
  • im:6912645
  • zgc:113207
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Involved in animal organ development; digestive tract development; and negative regulation of apoptotic process. Human ortholog(s) of this gene implicated in maple syrup urine disease. Is expressed in brain; heart; liver; neural tube; and trunk musculature. Orthologous to human PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Lu et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppm1kb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
maple syrup urine disease Alliance ?Maple syrup urine disease, mild variant 615135
Associated With ppm1kb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000222 PPM-type phosphatase, divalent cation binding
Domain IPR001932 PPM-type phosphatase-like domain
Homologous_superfamily IPR036457 PPM-type phosphatase-like domain superfamily
Domain Details Per Protein
Protein Length PPM-type phosphatase, divalent cation binding PPM-type phosphatase-like domain PPM-type phosphatase-like domain superfamily
UniProtKB:A0A8M2B6X8 242
UniProtKB:F6PA41 188
UniProtKB:A0A8M1P874 372
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations