ZFIN ID: ZDB-GENE-050306-56
Gene Name: angiotensin II receptor, type 2
Gene Symbol: agtr2    Nomenclature History

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Previous Name: zgc:113016

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have angiotensin type II receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; inflammatory response; and positive regulation of blood vessel diameter. Predicted to localize to plasma membrane. Is expressed in several structures, including blood vasculature; post-vent region; posterior lateral plate mesoderm; trunk; and vascular cord. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2).
Genome Resources: Alliance (1),  Gene:503772 (1),  Ensembl(GRCz11):ENSDARG00000035552 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024871Tg Transgenic Insertion Unknown Unknown DNA
sa40411 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH agtr2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH agtr2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function G protein-coupled receptor activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA agtr2-201 (1)    Ensembl 1875
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM agtr2 No data available
    MARKER RELATIONSHIPS
    agtr2 Contained in: [BAC] DKEY-125I10 (1) (order this)
    agtr2 Encodes: [EST] IMAGE:6895796 (1)
    [cDNA] MGC:113016 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013350 (1) 1840 nt
    Genomic GenBank:BX640521 (1) 126380 nt
    Select Tool
    Polypeptide UniProtKB:A2BHL6 (1) 360 aa
    Sequence Information (all 10)
    ORTHOLOGY for agtr2 ( Chr: 5 )
    CITATIONS (29)