ZFIN ID: ZDB-GENE-050306-12
Gene Name: sorting nexin 13
Gene Symbol: snx13    Nomenclature History

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Previous Name: zgc:113125

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol binding activity. Involved in negative regulation of cardiac muscle cell apoptotic process and negative regulation of extrinsic apoptotic signaling pathway. Predicted to localize to the integral component of membrane. Is expressed in brain; heart; liver; and skeletal muscle. Orthologous to human SNX13 (sorting nexin 13).
Genome Resources: Alliance (1),  Gene:503733 (1),  Ensembl(GRCz11):ENSDARG00000013828 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113125]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16799 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23409 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36749 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36750 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-snx13 N/A 1
    MO2-snx13 N/A 1
    DISEASE ASSOCIATED WITH snx13 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH snx13 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of cardiac muscle cell apoptotic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function phosphatidylinositol binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001683 Phox homologous domain
    Domain IPR003114 Phox-associated domain
    Domain IPR013937 Sorting nexin, C-terminal
    Domain IPR016137 RGS domain
    Homologous_superfamily IPR036305 RGS domain superfamily
    Homologous_superfamily IPR036871 PX domain superfamily
    Domain IPR037437 Sorting nexin-13, PX domain
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM snx13 No data available
    MARKER RELATIONSHIPS
    snx13 Encodes: [cDNA] MGC:113125 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013311 (1)
    Genomic GenBank:CABZ01071948 (1) 21380 bp
    Polypeptide UniProtKB:F1QM62 (1) 955 aa
    Sequence Information (all 20)
    ORTHOLOGY for snx13 ( Chr: 19 )
    CITATIONS (17)