ZFIN ID: ZDB-GENE-050302-15
Gene Name: dedicator of cytokinesis 7
Gene Symbol: dock7    Nomenclature History

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Previous Names: fb93h07, im:7145816, im:7157388, wu:fb93h07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Is expressed in central nervous system; optic vesicle; and retina. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 23. Orthologous to human DOCK7 (dedicator of cytokinesis 7).
Genome Resources: Alliance (1),  Gene:568817 (1),  Ensembl(GRCz11):ENSDARG00000078675 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7157388]
  6 figures (9 images) from Thisse et al., 2004 [IMAGE:7157391]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH dock7 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 23 Alliance Epileptic encephalopathy, early infantile, 23 615859
DISEASE ASSOCIATED WITH dock7 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process small GTPase mediated signal transduction (more)
Molecular Function guanyl-nucleotide exchange factor activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA dock7-201 (1)    Ensembl 6938
dock7-202 (1)    Ensembl 1225
ncRNA dock7-002 (1)    Ensembl 929
dock7-004 (1)    Ensembl 518
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM dock7 No data available
MARKER RELATIONSHIPS
dock7 Contained in: [BAC] CH211-208A5 (1)
dock7 Encodes: [EST] fb93h07, IMAGE:7145816, IMAGE:7157388 (1), IMAGE:7157391 (1)
[cDNA] MGC:162908 (1), MGC:171344 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001082861 (1)
Genomic GenBank:BX936431 (1) 127584 nt
Select Tool
Polypeptide UniProtKB:F1Q8Z1 (1) 2129 aa
Sequence Information (all 102)
ORTHOLOGY for dock7 ( Chr: 6 )
CITATIONS (21)