Gene

cltcb

ID
ZDB-GENE-050227-12
Name
clathrin, heavy chain b (Hc)
Symbol
cltcb Nomenclature History
Previous Names
  • fd07f11
  • im:7145213
  • wu:fd07f11
  • zgc:113234
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have clathrin light chain binding activity and structural molecule activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to localize to clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; and clathrin complex. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 56. Orthologous to human CLTC (clathrin heavy chain).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cltcb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant mental retardation 56 Alliance Mental retardation, autosomal dominant 56 617854
Associated With cltcb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR015348 Clathrin, heavy chain, linker, core motif
Family IPR016341 Clathrin, heavy chain
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR016025 Clathrin heavy chain, N-terminal
Repeat IPR000547 Clathrin, heavy chain/VPS, 7-fold repeat
Repeat IPR022365 Clathrin, heavy chain, propeller repeat
Domain Details Per Protein
Protein Length Armadillo-type fold Clathrin, heavy chain Clathrin, heavy chain, linker, core motif Clathrin heavy chain, N-terminal Clathrin, heavy chain, propeller repeat Clathrin, heavy chain/VPS, 7-fold repeat Tetratricopeptide-like helical domain superfamily
UniProtKB:F1R4U8 318
UniProtKB:E9QBV1 1677
UniProtKB:Q5EAQ7 89
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations