ZFIN ID: ZDB-GENE-050227-12
Gene Name: clathrin, heavy chain b (Hc)
Gene Symbol: cltcb    Nomenclature History

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Previous Names: fd07f11, im:7145213, wu:fd07f11, zgc:113234

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have clathrin light chain binding activity. Predicted to be involved in clathrin coat assembly; mitotic cell cycle; and receptor-mediated endocytosis. Predicted to localize to clathrin complex; clathrin-coated endocytic vesicle; and spindle. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 56. Orthologous to human CLTC (clathrin heavy chain).
Genome Resources: Alliance (1),  Gene:503600 (1),  Ensembl(GRCz11):ENSDARG00000090716 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7145213]
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cltcb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant mental retardation 56 Alliance Mental retardation, autosomal dominant 56 617854
DISEASE ASSOCIATED WITH cltcb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular protein transport (more)
Cellular Component clathrin-coated pit (more)
Molecular Function clathrin light chain binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cltcb-201 (1)    Ensembl 6350
cltcb-202 (1)    Ensembl 1347
cltcb-203 (1)    Ensembl 1308
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cltcb No data available
MARKER RELATIONSHIPS
cltcb Contained in: [BAC] CH211-217N8 (1)
cltcb Encodes: [EST] fd07f11, IMAGE:7145213 (1)
[cDNA] MGC:113234 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001194978 (1) 6365 nt
Genomic GenBank:CR848791 (1) 135392 nt
Select Tool
Polypeptide UniProtKB:E9QBV1 (1) 1677 aa
Sequence Information (all 22)
ORTHOLOGY for cltcb ( Chr: 15 )
CITATIONS (21)