ZFIN ID: ZDB-GENE-050224-2
Gene Name: connexin 34.5
Gene Symbol: cx34.5    Nomenclature History

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Previous Names: cx20a (1), gjaa (1), si:dkey-261a18.2, zgc:136235

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to localize to connexin complex. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human GJA4 (gap junction protein alpha 4).
Genome Resources: Alliance (1),  Gene:565892 (1),  Ensembl(GRCz11):ENSDARG00000069411 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12968 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cx34.5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cx34.5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell communication (more)
    Cellular Component cell junction (more)
    Molecular Function gap junction channel activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cx34.5-201 (1)    Ensembl 1328
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cx34.5 No data available
    MARKER RELATIONSHIPS
    cx34.5 Contained in: [BAC] DKEY-261A18 (1) (order this)
    [Fosmid] CH1073-265L12 (1)
    cx34.5 Encodes: [cDNA] MGC:136235 (1), MGC:173519 (1), MGC:191421 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030200 (1) 1344 nt
    Genomic GenBank:CR352322 (1) 59134 nt
    Select Tool
    Polypeptide UniProtKB:A7YYA8 (1) 298 aa
    Sequence Information (all 21)
    ORTHOLOGY for cx34.5 ( Chr: 20 )
    CITATIONS (21)