ZFIN ID: ZDB-GENE-050222-3
Gene Name: discs, large (Drosophila) homolog 1, like
Gene Symbol: dlg1l    Nomenclature History

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Previous Name: SAP-97B (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have phosphatase binding activity and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; endothelial cell proliferation; and protein localization to membrane. Predicted to colocalize with ionotropic glutamate receptor complex. Is expressed in retina; spinal cord; and tegmentum. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1).
Genome Resources: Alliance (1),  Gene:497648 (1),  Ensembl(GRCz11):ENSDARG00000102216 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu269]
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014997Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014998Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014999Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023752Tg Transgenic Insertion Unknown Unknown DNA
    la028829Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1431 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10085 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15931 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dlg1l HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dlg1l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament organization (more)
    Cellular Component basolateral plasma membrane (more)
    Molecular Function phosphatase binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript dlg1l-206 (1)    Ensembl 2598
    mRNA dlg1l-202 (1)    Ensembl 672
    dlg1l-204 (1)    Ensembl 6958
    dlg1l-205 (1)    Ensembl 2964
    ncRNA dlg1l-003 (1)    Ensembl 796
    dlg1l-004 (1)    Ensembl 614
    dlg1l-007 (1)    Ensembl 890
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dlg1l No data available
    MARKER RELATIONSHIPS
    dlg1l Contained in: [BAC] CH211-162E15 (1), CH211-257P7 (1), CH211-262K7 (1)
    dlg1l Encodes: [EST] eu269 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001012388 (1) 2662 nt
    Genomic GenBank:AL807799 (1) 175342 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IEK3 (1) 906 aa
    Sequence Information (all 60)
    ORTHOLOGY for dlg1l ( Chr: 2 )
    CITATIONS (22)