ZFIN ID: ZDB-GENE-050221-9
Gene Name: matrilin 3b
Gene Symbol: matn3b    Nomenclature History

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Previous Name: zgc:123028

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to be involved in growth plate cartilage chondrocyte morphogenesis. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Is expressed in hypochord and notochord. Human ortholog(s) of this gene implicated in multiple epiphyseal dysplasia 5; osteoarthritis; and osteochondrodysplasia. Orthologous to human MATN3 (matrilin 3).
Genome Resources: Alliance (1),  Gene:497645 (1),  Ensembl(GRCz11):ENSDARG00000069265 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 3 publications
Directly Submitted Expression Data: 4 figures (3 images) from Thisse et al., 2004 [IMAGE:7157032]
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24939 Point Mutation Unknown Premature Stop ENU
sa28147 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH matn3b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
multiple epiphyseal dysplasia 5 Alliance Epiphyseal dysplasia, multiple, 5 607078
?Spondyloepimetaphyseal dysplasia 608728
{Osteoarthritis susceptibility 2} 140600
DISEASE ASSOCIATED WITH matn3b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component collagen-containing extracellular matrix (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA matn3b-201 (1)    Ensembl 1144
matn3b-202 (1)    Ensembl 1484
matn3b-203 (1)    Ensembl 1352
matn3b-204 (1)    Ensembl 1099
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM matn3b No data available
MARKER RELATIONSHIPS
matn3b Contained in: [BAC] CH211-206K20 (1)
matn3b Encodes: [EST] IMAGE:7157032 (1)
[cDNA] MGC:123028 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001012385 (1) 1484 nt
Genomic GenBank:AL935163 158350 nt
Select Tool
Polypeptide UniProtKB:Q5NIW0 (1) 478 aa
Sequence Information (all 29)
ORTHOLOGY for matn3b ( Chr: 13 )
CITATIONS (20)