Gene

mical3b

ID

ZDB-GENE-050211-1

Name

microtubule associated monooxygenase, calponin and LIM domain containing 3b

Symbol

mical3b Nomenclature History

Previous Names

si:dkey-153k10.11
si:dkeyp-27e10.1

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have FAD binding activity; actin binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in actin filament depolymerization. Predicted to localize to nucleus. Is expressed in floor plate; hindbrain nucleus; octaval nerve motor nucleus; octaval nerve sensory nucleus; and spinal cord. Orthologous to human MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Xue et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mical3b Human Ortholog

No data available

Associated With mical3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR002938	FAD-binding domain
Domain	IPR022735	bMERB domain
Family	IPR050540	F-actin Monooxygenase Mical
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Length	bMERB domain	Calponin homology domain	CH domain superfamily	F-actin Monooxygenase Mical	FAD-binding domain	FAD/NAD(P)-binding domain superfamily	Zinc finger, LIM-type
UniProtKB:F1QWK4 InterPro
UniProtKB:A0A8M9PRL9 InterPro	1572
UniProtKB:A0A8M9PRL3 InterPro	1734
UniProtKB:A0A8M9PV05 InterPro	1572
UniProtKB:A0A8M9PHR6 InterPro	1698
UniProtKB:A0A8M9Q8P9 InterPro	1699
UniProtKB:A0A8M9PY14 InterPro	1540
UniProtKB:A0A8M9PXR3 InterPro	1709
UniProtKB:A0A8M9Q0Z6 InterPro	1735
UniProtKB:A0A8M9Q100 InterPro	1033
UniProtKB:A0A8M9PES7 InterPro	1735
UniProtKB:A0A8M9PET2 InterPro	1682
UniProtKB:A0A8M3ARC5 InterPro	1682
UniProtKB:A0A8M9Q689 InterPro	1709
UniProtKB:A0A8M9QBR6 InterPro	1734
UniProtKB:A0A8M3AYP9 InterPro	1699
UniProtKB:A0A8M9Q4D5 InterPro	1698

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mical3b-201 (1) Ensembl	Ensembl	5,964 nt	Select Tool
mRNA	mical3b-202 (1) Ensembl	Ensembl	493 nt	Select Tool
mRNA	mical3b-203 (1) Ensembl	Ensembl	5,885 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations