ZFIN ID: ZDB-GENE-050208-525
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Gene Name: platelet-derived growth factor beta polypeptide a
Gene Symbol: pdgfba
Previous Names: pdgfb, sb:eu1033, si:ch211-79m20.1, si:dkey-261d11.1
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2005 [eu1033]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  axial vasculature, diencephalon, floor plate, head blood vessel (all 11) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-pdgfba (1), MO2-pdgfba (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pdgfba HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
basal ganglia calcification Basal ganglia calcification, idiopathic, 5 615483
familial meningioma Meningioma, SIS-related 607174
Dermatofibrosarcoma protuberans 607907
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of DNA replication (more)
Cellular Component membrane (more)
Molecular Function growth factor activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000072 (1)
  • InterPro:IPR006782 (1)
  • InterPro:IPR023581 (1)
  • InterPro:IPR029034 (1)
    		•
  • PROSITE:PS00249 (1)
  • PROSITE:PS50278 (1)
    		•
  • Pfam:PF00341 (1)
  • Pfam:PF04692 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdgfba-001 (1) 1195
    Select Tool
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfba
    Tg(UAS:dnpdgfrb-YFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    pdgfbaContained in: [BAC] CH211-79M20 (1) (order this), DKEY-261D11 (1) (order this)
    pdgfbaEncodes: [EST] eu1033 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:DV584985 (1) 799bp
    Select Tool
    Genomic GenBank:AL929274 (1) 169459bp
    Select Tool
    Polypeptide UniProtKB:F1QS30 (1) 463aa
    Select Tool
    Sequence Information (all 8)
    OTHER pdgfba GENE PAGES
  • VEGA:OTTDARG00000017343 (1)
  • Ensembl(GRCz10):ENSDARG00000086778 (1)
    • ORTHOLOGY for pdgfba (Chr: 22)
    Species Symbol Chromosome Accession # Evidence
    Human PDGFB 22
  • Gene:5155
  • OMIM:190040
  • HGNC:8800
    		•  Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Pdgfb 15
  • MGI:97528
  • Gene:18591
    		•  Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (16)