ZFIN ID: ZDB-GENE-050208-525
Gene Name: platelet-derived growth factor beta polypeptide a
Gene Symbol: pdgfba
Previous Names: pdgfb, si:ch211-79m20.1, si:dkey-261d11.1
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  axial vasculature, head blood vessel, heart, intersegmental vessel (all 7) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-pdgfba (1), MO2-pdgfba (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pdgfba HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
basal ganglia calcification Basal ganglia calcification, idiopathic, 5 615483
familial meningioma Meningioma, SIS-related 607174
Dermatofibrosarcoma protuberans 607907
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of DNA replication (more)
Cellular Component membrane (more)
Molecular Function growth factor activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000072 (1)
  • InterPro:IPR006782 (1)
  • InterPro:IPR023581 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00249 (1)
  • PROSITE:PS50278 (1)
  • Pfam:PF00341 (1)
  • Pfam:PF04692 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdgfba-001 (1) 1195
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfba
    Tg(UAS:dnpdgfrb-YFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    pdgfba Contained in: [BAC] CH211-79M20 (1) (order this), DKEY-261D11 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688601 (1) 2693 bp
    Genomic GenBank:AL929274 (1) 169459 bp
    Select Tool
    Polypeptide UniProtKB:F1QP61 (1) 468 aa
    Sequence Clusters UniGene:120249 (1)
    Sequence Information (all 15)
    OTHER pdgfba GENE PAGES
  • Gene:565324 (1)
  • VEGA:OTTDARG00000017343 (1)
  • Ensembl(Zv9):ENSDARG00000086778 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish pdgfba 22  
    Human PDGFB 22 (22q13.1)
  • OMIM:190040
  • Gene:5155
  • Mouse Pdgfb 15 ( 37.85 cM)
  • MGI:97528
  • Gene:18591
  • Orthology Details
    CITATIONS (16)