ZFIN ID: ZDB-GENE-050208-525
Gene Name: platelet-derived growth factor beta polypeptide a
Gene Symbol: pdgfba
Previous Names: pdgfb, sb:eu1033, si:ch211-79m20.1, si:dkey-261d11.1
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2005 [eu1033]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  axial vasculature, diencephalon, floor plate, head blood vessel (all 11) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Targeting reagents: MO1-pdgfba (1), MO2-pdgfba (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pdgfba HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
basal ganglia calcification Basal ganglia calcification, idiopathic, 5 615483
familial meningioma Meningioma, SIS-related 607174
Dermatofibrosarcoma protuberans 607907
GENE ONTOLOGY 
Ontology GO Term
Biological Process regulation of DNA replication (more)
Cellular Component membrane (more)
Molecular Function growth factor activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000072 (1)
  • InterPro:IPR006782 (1)
  • InterPro:IPR023581 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00249 (1)
  • PROSITE:PS50278 (1)
  • Pfam:PF00341 (1)
  • Pfam:PF04692 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdgfba-001 (1) 1195
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfba
    Tg(UAS:dnpdgfrb-YFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    pdgfbaContained in: [BAC] CH211-79M20 (1) (order this), DKEY-261D11 (1) (order this)
    pdgfbaEncodes: [EST] eu1033 (1)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:DV584985 (1) 799bp
    Genomic GenBank:AL929274 (1) 169459bp
    Select Tool
    Polypeptide UniProtKB:F1QS30 (1) 463aa
    Sequence Clusters UniGene:120249 (1)
    Sequence Information (all 11)
    OTHER pdgfba GENE PAGES 
  • Gene:565324 (1)
  • VEGA:OTTDARG00000017343 (1)
  • Ensembl(GRCz10):ENSDARG00000086778 (1)
  • ORTHOLOGY for pdgfba (Chr: 22) 
    Species Symbol Chromosome Accession # Evidence
    Human PDGFB 22
  • Gene:5155
  • OMIM:190040
  • HGNC:8800
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Pdgfb 15
  • MGI:97528
  • Gene:18591
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (17)