ZFIN Gene: pdgfba

ZFIN ID: ZDB-GENE-050208-525

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Gene Name:	platelet-derived growth factor beta polypeptide a
Gene Symbol:	pdgfba
Previous Names:	pdgfb, si:ch211-79m20.1, si:dkey-261d11.1
Location:	Chr: 22 Details
Nomenclature History

Gene Name:

platelet-derived growth factor beta polypeptide a

Gene Symbol:

pdgfba

Previous Names:

pdgfb, si:ch211-79m20.1, si:dkey-261d11.1

Location:

Chr: 22 Details

Nomenclature History

GENE EXPRESSION
All Expression Data:	4 figures from 4 publications
Wild-type Stages, Structures:	Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
	axial vasculature , head blood vessel , heart , intersegmental vessel (all 7)

GENE EXPRESSION

All Expression Data:

4 figures from 4 publications

Wild-type Stages, Structures:

Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)

axial vasculature, head blood vessel, heart, intersegmental vessel (all 7) expand

PHENOTYPE

Phenotype of Human Orthologue	OMIM Phenotype ID
Basal ganglia calcification, idiopathic, 5	615483
Dermatofibrosarcoma protuberans	607907
Meningioma, SIS-related	607174

GENE ONTOLOGY

Ontology	GO Term
Biological Process	regulation of DNA replication (more)
Cellular Component	membrane (more)
Molecular Function	growth factor activity (more)

GO Terms (all 17)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000072 (1) InterPro:IPR006782 (1) InterPro:IPR023581 (1) InterPro:IPR029034 (1)	PROSITE:PS00249 (1) PROSITE:PS50278 (1)	Pfam:PF00341 (1) Pfam:PF04692 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	pdgfb-001 (1)	1195	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

pdgfba Contained in:

[BAC] CH211-79M20 (1) (order this), DKEY-261D11 (1) (order this)

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_688601 (1)	2693 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:AL929274 (1)	169459 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A088AWM4 (1)	183 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:120249 (1)

Type

Accession #

Length (bp/aa)

Analysis

RNA

RefSeq:XM_688601 (1)

2693 bp

Select Tool

ZFIN BLAST

NCBI BLAST

Ensembl

UCSC BLAT

Vega

Genomic

GenBank:AL929274 (1)

169459 bp

Select Tool

MegaBLAST

Ensembl

Polypeptide

UniProtKB:A0A088AWM4 (1)

183 aa

Select Tool

ZFIN BLAST

SIB BLAST

Ensembl Protein Blast

Vega Protein Blast

Sequence Clusters

UniGene:120249 (1)

ORTHOLOGY

				Evidence
Species	Symbol	Chr (Position)	Accession #	AA	CL
Zebrafish	pdgfba	22
Human	PDGFB	22 (22q13.1)	OMIM:190040 Gene:5155
Mouse	Pdgfb	15 ( 37.85 cM)	MGI:97528 Gene:18591
Orthology Details