Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050208-525
Gene Name: platelet-derived growth factor beta polypeptide
Gene Symbol: pdgfb
Previous Names: si:ch211-79m20.1, si:dkey-261d11.1
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  axial vasculature, head blood vessel, heart, intersegmental vessel (all 7) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-pdgfb (1), MO2-pdgfb (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Basal ganglia calcification, idiopathic, 5 615483
Dermatofibrosarcoma protuberans 607907
Meningioma, SIS-related 607174
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of DNA replication (more)
Cellular Component membrane (more)
Molecular Function growth factor activity (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000072 (1)
  • InterPro:IPR006782 (1)
  • InterPro:IPR023581 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00249 (1)
  • PROSITE:PS50278 (1)
  • Pfam:PF00341 (1)
  • Pfam:PF04692 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdgfb-001 (1) 1195
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfb
    Tg(UAS:dnpdgfrb-YFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    pdgfb Contained in: [BAC] CH211-79M20 (1) (order this), DKEY-261D11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_688601 (1) 2693 bp
    Genomic GenBank:AL929274 (1) 169459 bp
    Select Tool
    Polypeptide UniProtKB:Q1MTA0 (1) 183 aa
    Sequence Clusters UniGene:82403 (1)
    Sequence Information (all 10)
    OTHER pdgfb GENE PAGES
  • Gene:565324 (1)
  • VEGA:OTTDARG00000017343 (1)
  • Ensembl(Zv9):ENSDARG00000086778 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish pdgfb 22  
    Human PDGFB 22 (22q13.1)
  • OMIM:190040
  • Gene:5155
  • Mouse Pdgfb 15 ( 37.85 cM)
  • MGI:97528
  • Gene:18591
  • Orthology Details
    CITATIONS (15)