Gene

shoc2

ID
ZDB-GENE-050208-523
Name
SHOC2 leucine rich repeat scaffold protein
Symbol
shoc2 Nomenclature History
Previous Names
  • si:ch211-159c12.3
  • si:ch211-197i12.3
  • zgc:152956
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have protein phosphatase binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction. Predicted to localize to nucleus and protein phosphatase type 1 complex. Orthologous to human SHOC2 (SHOC2 leucine rich repeat scaffold protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Jang et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from Jang et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With shoc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Noonan syndrome-like disorder with loose anagen hair 1 Alliance Noonan syndrome-like with loose anagen hair 1 607721
Associated With shoc2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype
UniProtKB:Q1L8Y7 561
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations