Gene

shoc2

ID
ZDB-GENE-050208-523
Name
SHOC2 leucine rich repeat scaffold protein
Symbol
shoc2 Nomenclature History
Previous Names
  • si:ch211-159c12.3
  • si:ch211-197i12.3
  • zgc:152956
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have protein phosphatase 1 binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction. Predicted to localize to nucleus and protein phosphatase type 1 complex. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 1. Orthologous to human SHOC2 (SHOC2 leucine rich repeat scaffold protein).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 1 from Jang et al., 2018
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from Jang et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With shoc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Noonan syndrome-like disorder with loose anagen hair 1 Alliance Noonan syndrome-like with loose anagen hair 1 607721
Associated With shoc2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:Q1L8Y7 561
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations